COMPUTATIONAL AND STRUCTURAL BASED APPROACH TO IDENTIFY MALIGNANT NONSYNONYMOUS SINGLE NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH CDK4 GENE.

Computational and structural based approach to identify malignant nonsynonymous single nucleotide polymorphisms associated with CDK4 gene.

Cycline-dependent kinase 4 (CDK4), an enzyme of the cycline dependent or Ser/Thr protein kinase family, plays a role in cell cycle progression (G1 phase) by phosphorylating a tumor suppressor protein called pRB.Alteration of this enzyme due Heatshrink to missense mutation/ nonsynonymous single nucleotide polymorphisms (nsSNPs) are responsible for v

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Emotional Dysregulation in Adolescents: Implications for the Development of Severe Psychiatric Disorders, Substance Abuse, and Suicidal Ideation and Behaviors

Well-tuned Bird Bath emotional regulation is fundamental for human life and psychological well-being.Negative physiological emotions are counterbalanced by positive ones, and this equilibrium is the mainstay of human physiological affective states.However, this mechanism may sometimes become dysfunctional when negative emotions are not correctly co

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Improving development profit by using reservoir based completion

Implementation of well completions enabling multiple hydrocarbon reservoirs to be Bird Bath produced by a single well can save production cost and enhance recovery.Aiming at the characteristics of the three types of oil and gas reservoirs in the Jabung block in Indonesia, namely, gas cap oil-rim reservoirs, multiple hydrocarbon reservoirs, and hete

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